Julio Fernandez is a tenured professor at Columbia University in the Department of Biological Sciences. He trained in Physics (B.S.) and Physiology (Ph.D.) and he is a world leader in the field of single molecule biology, and the founder of the field of protein mechanics. He has taught at the University of Pennsylvania Medical School and at the Medical School of the Mayo Clinic, where he was Chair of the Department of Physiology and Biophysics. He is also an international lecturer teaching weeklong workshops in South Africa, China, Israel and Spain. He has been cited about 13,000 times for his work, with an h factor approaching sixty. He has been awarded prizes by the Alexander von Humboldt Foundation in Germany, and by the Biophysical Society in the US. While at the Mayo Clinic, he was the founder of a start up Drug Delivery Company called Tacora Corporation and patented delivery technologies based on mimicking exocytosis. More recently he has worked with Columbia Ventures to patent and license technologies related to the development of instrumentation for single molecule enzymatic assays, and enzyme discovery using the rapidly growing database of enzyme sequences from extant organisms. A developing interest is in the use of biological algorithms to analyze social data obtained from Google trends database. A current major effort is in the development of a large-scale computer model to integrate the physics and chemistry of the giant elastic protein titin, to predict the severity of dilated cardiomyopathies from the rapidly growing patient database of titin mutations.